Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) MBS439012 from MyBioSource.com

Product Specs
ItemCaldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker)
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS439012
Quantity0.1 mg
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman
TargetCaldesmon
IsotypeIgG
Molecular WeightAntigen: 150kDa
CloneCALD1/820 + h-CALD
HostMouse
ImmunogenRecognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction
NCBI Full Gene Namecaldesmon 1
NCBI Gene AliasesCDM, HCAD, NAG22, L-CAD, LCAD, H-CAD
ClonalityMonoclonal